Immune response in lung cancer mouse model mimics human anti-Hu reactivity
نویسندگان
چکیده
منابع مشابه
Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras
Injecting human peripheral blood mononuclear cells into severe combined immunodeficient (SCID) mice results in long-term engraftment of human lymphocytes, of which > 98% are phenotypically mature, activated T cells. Here we have characterized the human T cells that populate such hu-PBL-SCID chimeras. We report that these human T cells do not mobilize Ca2+ after CD3 stimulation, i.e., their T ce...
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ژورنال
عنوان ژورنال: Journal of Neuroimmunology
سال: 2009
ISSN: 0165-5728
DOI: 10.1016/j.jneuroim.2009.08.014